Cyclophosphamide is a strong medication reserved for severe or rapidly progressing disease, often the lungs. Bladder protection and fertility are discussed before you start.
Cyclophosphamide is a potent immunosuppressant used for severe myositis, particularly rapidly progressive lung disease, when strong and fast control is needed. It is usually given for a limited course to bring the disease under control, then followed by a gentler maintenance medication. It is used in myositis based on specialist experience and evidence rather than a formal Canadian myositis indication.
Brings serious or organ-threatening myositis under control when other options are not enough.
A key option for rapidly progressive myositis-related lung involvement.
Used for a defined course rather than indefinitely.
Gains control, then hands over to a gentler long-term medication.
Your doctor prescribed this because the expected benefits outweigh the risks for your situation. Here is the honest, full picture.
Because cyclophosphamide can affect fertility and irritate the bladder, your team discusses fertility preservation and uses hydration and a bladder-protecting medicine before and during treatment. It is used for the shortest effective course.
Cyclophosphamide must not be used in pregnancy, since it can harm the baby, and it can affect fertility. Effective contraception is essential during treatment. If you may want children, talk with your team about fertility preservation before you start.
This guide is for education, not medical advice. Myositis treatment is individual, and many of these medications are used based on specialist experience and evidence rather than a formal Canadian myositis indication. Never start, stop, or change a medication without your own doctor. Your doses and choices are decided with your care team at the Centre.