Oral bisphosphonates must be taken on an empty stomach with a full glass of water, staying upright afterward. A dental check is done before starting.
Bisphosphonates slow the breakdown of bone. Because long-term prednisone weakens bone and raises fracture risk, a bisphosphonate is often prescribed to prevent and treat steroid-induced osteoporosis. Common options are risedronate (Actonel) and alendronate (Fosamax) taken by mouth, or zoledronic acid given once a year by infusion.
Protects the spine and hip against the bone loss that long-term steroids cause.
Decades of evidence for preventing and treating osteoporosis.
Weekly or monthly tablets, or a once-yearly infusion.
Available as low-cost generics.
Your doctor prescribed this because the expected benefits outweigh the risks for your situation. Here is the honest, full picture.
Bisphosphonates are generally avoided in pregnancy and breastfeeding, since they stay in bone for a long time. Tell your doctor if you are pregnant or planning, so bone protection can be reviewed.
This guide is for education, not medical advice. Myositis treatment is individual, and many of these medications are used based on specialist experience and evidence rather than a formal Canadian myositis indication. Never start, stop, or change a medication without your own doctor. Your doses and choices are decided with your care team at the Centre.